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Fig. 6 | BMC Genomics

Fig. 6

From: circ_0038718 promotes colon cancer cell malignant progression via the miR-195-5p/Axin2 signaling axis and also effect Wnt/β-catenin signal pathway

Fig. 6

circ_0038718 activates Wnt/β-catenin signaling pathway via the circ_0038718/miR-195-5p/Axin2 axis. (A) qRT-PCR was conducted to detect the expression of circ_0038718, miR-195-5p and Axin2 in each group; (B) Western blot was performed to determine the protein expression of Axin2 and the key proteins of the Wnt/β-catenin signaling pathway; CC cell viability and proliferative ability were assessed via (C) MTT assay; (D-E) Transwell assay was conducted to evaluate CC cell migratory and invasive capacities (100×). * p < 0.05

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BMC Genomics

ISSN: 1471-2164

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