Fig. 7From: circ_0038718 promotes colon cancer cell malignant progression via the miR-195-5p/Axin2 signaling axis and also effect Wnt/β-catenin signal pathwaycirc_0038718 silencing reduces CC cell tumorigenesis in vivo. (A) Tumor cell tumorigenesis of nude mice in all groups was identified; (B) Average tumor weight of nude mice after 5 weeks; (C) Tumor volume of nude mice in all groups for 5 weeks; (D) qRT-PCR was performed to detect the expression of circ_0038718, miR-195-5p and Axin2 in tumor tissue of nude mice; (E) Immunohistochemistry was conducted to assess the expression of Axin2, β-catenin, c-Myc and cyclin D1 in tumor tissue (400×). * p < 0.05Back to article page