Table 3 Chromosomal locations of the mapped Quantitative Trait Loci (QTL) at 50% genome wide significant threshold level and found to be associated with polyp counts in SB1, SB2, SB3, Colon and total polyps in the entire intestines (SB1–3 and colon) regions of different CC lines. QTL associated with polyp counts detected on different chromosomal regions. Experiment- confidence intervals (CI) of significance at *P% of 90 and 95% levels are presented for each trait, accordingly
Trait | Chromosome location | Peak | CI 90% Size (Mb) [Genes] | CI 95% Size (Mb) [Genes] |
|---|---|---|---|---|
SB1 | chr7 | 87.273 | 79.392–92.031 | 77.912–93.918 |
(12.639) | (16.006) | |||
[260] | [309] | |||
chr7 | 103.731 | 94.877–110.206 | 93.967–112.342 | |
(15.329) | (18.375) | |||
[582] | [615] | |||
chr6 | 145.956 | 137.764–147.736 | 136.531–148.381 | |
(9.972) | (11.85) | |||
[138] | [167] | |||
chr14 | 73.794 | 64.12–82.311 | 63.807–83.451 | |
(18.191) | (19.644) | |||
[296] | [312] | |||
SB2 | chr6 | 146.284 | 138.715–147.765 | 137.334–148.218 |
(9.05) | (10.884) | |||
[129] | [147] | |||
chr12 | 113.669 | 104.039119.56 | 103.67–120.723 | |
(15.521) | (17.053) | |||
[620] | [642] | |||
SB3 | chr3 | 12.197 | 6.161–21.878 | 4.711–22.198 |
(15.717) | (17.487) | |||
[174] | [190] | |||
chr4 | 140.994 | 131.573–150.502 | 131.067–150.94 | |
(18.929) | (19.873) | |||
[667] | [677] | |||
chr7 | 145.941 | 138.321–152.901 | 136.883–154.414 | |
(14.58) | (17.531) | |||
[244] | [254] | |||
chr16 | 73.271 | 68.142–79.809 | 65.692–82.693 | |
(11.667) | (17.001) | |||
[271] | [370] | |||
chr16 | 53.511 | 43.867–63.054 | 43.524–63.477 | |
(19.187) | (19.953) | |||
[266] | [272] | |||
chr18 | 40.491 | 30.571–49.528 | 30.483–50.356 | |
(18.957) | (19.873) | |||
[379] | [392] | |||
Colon | chr1 | 34.282 | 33.429–35.455 | 32.859–35.727 |
(2.026) | (2.868) | |||
[35] | [43] | |||
Total polyps | chr3 | 11.823 | 3.155–21.794 | 2.322–21.835 |
(18.639) | (19.513) | |||
[199] | [199] | |||
chr4 | 126.165 | 124.866–127.097 | 123.887–127.464 | |
(2.231) | (3.577) | |||
[74] | [119] | |||
chr6 | 146.233 | 138.363–147.629 | 137.058–148.081 | |
(9.266) | (11.023) | |||
[130] | [146] | |||
chr10 | 19.133 | 10.259–27.523 | 9.325–28.692 | |
(17.264) | (19.367) | |||
[228] | [247] | |||
chr14 | 74.654 | 67.9751–78.268 | 66.108–82.316 | |
(10.2929) | (16.208) | |||
[176] | [258] | |||
chr18 | 10.631 | 6.347–16.314 | 5.249–17.996 | |
(9.967) | (12.747) | |||
[149] | [174] |