Fig. 2
From: Expanding the potential genes of inborn errors of immunity through protein interactions
Discovery Pathway 1 reveals IEI candidates by analyzing transcriptional regulation and post-translational modifications of known IEI genes. AÂ Number of confirmed IEI genes in respective IUIS tables as defined by the phenotype that their variants cause. BÂ Number of candidate IEI genes in tables classified by their interactions with known IEI genes. For A and B, only primary tables were utilized. CÂ Number of known IEI genes and their respective modifications. DÂ Number of candidate IEI genes that transcriptionally regulate IEI genes, are regulated by IEI genes, and PTMs to/from IEI genes