From: Brain-derived neurotrophic factor gene variants and obesity in former smokers
N (%) | Smoke exposure | ||||
---|---|---|---|---|---|
n = 15,072 | Never (n = 12,852) | Former (n = 1233) | Current (n = 987) | P§ | |
Sex | < 0.001 | ||||
 Male | 3169 (21.0) | 1263 (9.8) | 1037 (84.1) | 869 (88.0) | |
 Female | 11,903 (79.0) | 11,589 (90.2) | 196 (15.9) | 118 (12.0) | |
Age (years) | < 0.001 | ||||
 50–59 | 7474 (49.6) | 6807 (53.0) | 278 (22.5) | 389 (39.4) | |
 60–69 | 5794 (38.4) | 4678 (36.4) | 648 (52.6) | 468 (47.4) | |
  ≥ 70 | 1804 (12.0) | 1367 (10.6) | 307 (24.9) | 130 (13.2) | |
Education | < 0.001 | ||||
 ≦Primary school | 6025 (40.0) | 5184 (40.3) | 473 (38.4) | 368 (37.3) | |
 Middle school | 7762 (51.5) | 6638 (51.6) | 615 (49.9) | 509 (51.6) | |
  ≥ College school | 1285 (8.5) | 1030 (8.0) | 145 (11.8) | 110 (11.1) | |
Income†| < 0.001 | ||||
  < 10000Yuan | 4935 (32.7) | 4356 (33.9) | 307 (24.9) | 272 (27.6) | |
 10,000-14999Yuan | 6711 (44.5) | 5829 (45.4) | 525 (42.6) | 357 (36.2) | |
  ≥ 15000Yuan | 2723 (16.4) | 2106 (16.4) | 337 (27.3) | 280 (28.4) | |
 Don’t know | 703 (4.7) | 561 (4.4) | 64 (5.2) | 78 (7.9) | |
Physical activity | < 0.001 | ||||
 Low | 1237 (8.2) | 1073 (8.3) | 63 (5.1) | 101 (10.2) | |
 Medium | 5878 (39.0) | 4937 (38.4) | 502 (40.7) | 439 (44.5) | |
 High | 7957 (52.8) | 6842 (53.2) | 668 (54.2) | 447 (45.3) | |
Body Mass Index | < 0.001 | ||||
  < 18.5 | 743 (4.9) | 622 (4.8) | 42 (3.4) | 79 (8.0) | |
 18.5–23.9 | 7360 (48.8) | 6224 (48.4) | 579 (47.0) | 557 (56.4) | |
 24–27.9 | 5305 (35.2) | 4536 (35.3) | 491 (39.8) | 278 (28.2) | |
  ≥ 28 | 1664 (11.0) | 1470 (11.4) | 121 (9.8) | 73 (7.4) | |
Central obesity‡ | < 0.001 | ||||
 Yes | 7868 (52.2) | 7090 (55.2) | 492 (39.9) | 286 (29.0) | |
 No | 7204 (47.8) | 5762 (44.8) | 741 (60.1) | 701 (71.0) | |
Rs6265 | 0.85 | ||||
 AA | 3988 (26.5) | 3391 (26.4) | 335 (27.2) | 262 (26.5) | |
 GA | 7571 (50.2) | 6467 (50.3) | 620 (50.3) | 484 (49.0) | |
 GG | 3513 (23.3) | 2994 (23.3) | 278 (22.5) | 241 (24.4) | |
Rs4923457 | 0.39 | ||||
 TT | 3606 (23.9) | 3065 (23.8) | 314 (25.5) | 227 (23.0) | |
 AT | 7487 (49.7) | 6402 (49.8) | 606 (49.1) | 479 (48.5) | |
 AA | 3979 (26.4) | 3385 (26.3) | 313 (25.4) | 281 (28.5) | |
Rs11030104 | 0.44 | ||||
 GG | 3999 (26.5) | 3412 (26.5) | 322 (26.1) | 265 (26.8) | |
 AG | 7584 (50.3) | 6465 (50.3) | 642 (52.1) | 477 (48.3) | |
 AA | 3489 (23.1) | 2975 (23.1) | 269 (21.8) | 245 (24.8) | |
Rs6484320 | 0.92 | ||||
 TT | 3868 (25.7) | 3291 (25.6) | 325 (26.4) | 252 (25.5) | |
 TA | 7564 (50.2) | 6456 (50.2) | 620 (50.3) | 488 (49.4) | |
 AA | 3640 (24.2) | 3105 (24.2) | 288 (23.4) | 247 (25.0) |