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Fig. 2 | BMC Genomics

Fig. 2

From: Up-regulation of apoptotic- and cell survival-related gene pathways following exposures of western corn rootworm to B. thuringiensis crystalline pesticidal proteins in transgenic maize roots

Fig. 2

Prediction and filtering of putatively differentially expressed transcripts among susceptible Diabrotica virgifera virgifera larvae exposed to maize roots expressing Bacillus thuringiensis (Bt) pesticidal proteins. A) Correlation between Log2(fold-change) estimates between DESeq2 and EdgeR statistical packages for predicted differentially-expressed transcripts among larvae exposed roots that express Cry3Bb1 (T8; VT TriplePro® (VT3) hybrid) or Gpp34/Tpp35Ab1 (T5; Herculex® XTRA (Hx) hybrid) compared to non-Bt control maize (T7; Cn). Venn diagrams indicate the number of predicted differentially-expressed transcripts by DESeq2 and EdgeR surpassing significance thresholds (FDR ≤ 0.05), where the intersections (green up-regulated; red down-regulated) indicate those significant within both analyses. B) Comparison of differentially expressed transcripts between Bt and entomopathogen treatments, Heterorhabditis bacteriophora (Hb) and Metarhizium anisopliae (Ma). Differentially expressed transcripts within the intersection of Bt and entomopathogen treatments were subtracted to arrive at final filtered sets for Cry3Bb1 (T8; VT3) and Gpp34/Tpp35Ab1 (T5; Hx) maize treatments (green up-regulated; red down-regulated)

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