Fig. 6
From: Gene co-expression network analysis in zebrafish reveals chemical class specific modules
Validation of cyp1a network neighborhood genes identified from the network analysis. Comparative gene expression of cyp1a and selected cyp1a network neighborhood genes in 48-hpf wildtype and AHR2 mutant zebrafish developmentally exposed to 0.1% DMSO or 1 ng/mL TCDD (n = 3–4 biological replicates). Beta-actin was used as the normalization control. Error bars indicate SD of the mean. * = p-value < 0.05 compared to the wildtype vehicle control (DMSO). Statistical significance was determined using a Kruskal Wallis rank sum test followed by a Dunnett’s test for data that were not normal (NA_732), or a two-way ANOVA followed by a Tukey test for data that were normal (all other genes)