Fig. 4

Acrylamide exposure alters the mouse seminal vesicle transcriptome. A Differentially regulated genes in the mouse seminal vesicles were identified following acrylamide treatment using DEseq2 and were filtered based on those genes with a fold-change ≥1.5 or ≤ 0.67 and an adjusted p (p.adj) value ≤0.1. These data are represented using A Principal Component Analysis plot of transcriptomic data from acrylamide (red) and control (blue) samples to identify transcriptome wide changes across biological replicates, and B-C plots to identify specific genes that meet the fold-change and p.adj threshold criteria. B Volcano plot comparing fold-change and –Log10 p.adj, and C MA plot comparing Log2 average abundance to Log2 fold-change. Red data points indicate genes that are higher in acrylamide treated samples, blue data points indicates genes higher in control samples, grey data points indicate genes that do not meet the fold-change and p.adj criteria. All graphical components were generated using Prism (version 9.0.0)