Fig. 2

Phylogenetic relationships of NBD components of carbohydrate ABC transporters from species of Mycobacterium genus. A Phylogenetic tree of Mycobacterium carbohydrate NBD components was inferred using a Maximum likelihood method and Jones-Taylor-Thornton (JTT) amino acid substitution model in MEGA-X. Proteins were named with the same NCBI locus tag as presented in Table 1. Sub-groups were colored for better visualization. Dark gray: M. tuberculosis complex group (MTBC); light gray: other pathogenic mycobacteria, no color: environmental species. The amino acid sequence of TTH_RS04955 from Thermus thermophilus, encoding a putative carbohydrate NBD, was used as an outgroup. B Structural superposition of the NBDs models showing the regions of each protein that showed differences identified in the amino acid sequence alignment when compared to the others (spheres). The models were built using SWISS-MODEL server [31] and the details of modelling are presented in the Additional file 1 (Table S2). The N-terminal of the proteins is marked but C-terminal is not appearing in the figure