Fig. 4

Phylogenetic relationships of SBP components of carbohydrate ABC transporters from species of Mycobacterium genus. A Phylogenetic tree of Mycobacterium carbohydrate SBP components. The tree was inferred using a Maximum likelihood method and Whelan and Goldman (WAG) amino acid substitution model in MEGA-X. Dark gray: M. tuberculosis complex group (MTBC), light gray: other pathogenic mycobacteria, no color: environmental species. The amino acid sequence of TTH_RS04975 from Thermus thermophilus was used as an outgroup. B Crystallographic structures of UspC (PDB code: 5K2X) and UgpB (PDB code: 4MFI), and structural models of LpqY and Rv2041c were used for representation of regions that showed variation. Regions of amino acid insertion/deletion are represented in colored spheres