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Table 1 Top 20 genes with the highest differential expression between PP and MP > 3 cows. Positive fold change (FC), more highly expressed in PP cows; negative FC (shaded), more highly expressed in MP > 3 cows

From: Comparison of the transcriptome in circulating leukocytes in early lactation between primiparous and multiparous cows provides evidence for age-related changes

Gene Symbol

Gene name

logFC

adj.p.value

NELL2

neural EGFL like

−1.581

1.40E-63

ZNF462

zinc finger protein 462

1.931

1.79E-38

PLCL1

phospholipase C like 1 (inactive)

1.042

2.45E-37

IGF2BP3

insulin like growth factor 2 mRNA binding protein 3

2.268

6.36E-37

CNTNAP1

contactin associated protein 1

1.675

2.85E-35

SOX13

SRY-box transcription factor 13

1.925

8.17E-35

BLK

BLK proto-oncogene, Src family tyrosine kinase

0.881

1.23E-32

MYBL1

MYB proto-oncogene like 1

−0.771

1.93E-32

CD163L1

CD163 molecule like 1

1.463

6.55E-32

WNT5A

Wnt family member 5A

2.673

2.56E-31

SCRN1

secernin 1

1.129

5.03E-31

LOC515828

uncharacterised

1.207

6.12E-30

CSPG4

chondroitin sulfate proteoglycan 4

2.831

8.30E-30

DBN1

drebrin 1

0.942

1.95E-29

PTPRK

protein tyrosine phosphatase receptor type K

−3.301

2.00E-29

LAMA4

laminin subunit alpha 4

2.998

4.15E-29

TCAF1

TRPM8 channel associated factor 1

1.050

1.17E-28

LOC751811

WC1 isolate CH211

1.389

2.85E-28

SOX4

SRY-box transcription factor 4

0.820

3.69E-28

LOC104969122

uncharacterised

−1.396

9.97E-28