Fig. 2

Heatmap of significantly expressed miRNA microarray expression profile in the sheep model for lung fibrosis. The expression level of each miR was presented as fold-change relative to the control/saline group. Average intensity from the 21 replicates were taken for each miRNA probes tested for bleomycin and saline/control lung segments. Student’s t-test was performed and p < 0.01 was considered statistically significant. Hierarchical clustering was performed by applying One minus Pearson correlation to cluster differentially expressed miRNAs. Blue indicates under expression and red indicates over expression