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Fig. 5 | BMC Genomics

Fig. 5

From: RNAseq analysis of treatment-dependent signaling changes during inflammation in a mouse cutaneous wound healing model

Fig. 5

Arachadonic Acid/prostaglandin/leukotriene pathway analysis of treatment-induced changes in the RNA levels at 24 h post-injury. RNA levels were quantified by RNAseq, compared between the diclofenac-treated wounds vs control (upper left panel) and the Tr14-treated wound vs control (lower left panel), and then mapped to the major enzymes in the eicosanoid pathway using KEGG [16]. Red shading indicates the transcript is elevated relative to its control, yellow shading indicates the transcript is reduced relative to control. Proinflammatory pathways are marked with solid line, proresolution pathways marked with dashed line. Numerical fold changes are reported in right panel for selected DEGs in the COX/LOX pathway. All time points are reported in Supplementary Figs. 1-6

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