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Fig. 1 | BMC Genomics

Fig. 1

From: Role of DNA methylation on the association between physical activity and cardiovascular diseases: results from the longitudinal multi-ethnic study of atherosclerosis (MESA) cohort

Fig. 1

DNA methylation loci associated with PA and CVD. Representative volcano plots show the significant DNA methylation loci associated with continuous PA variable (a) and binary CVD outcome (b). DNA methylation loci were denoted as dots in red (significant loci) or in cyan (non-significant loci) according to the FDR cut-off value (0.05). The horizontal dashed line represents where p-value is 0.05. Venn diagram shows the overlapped 23 DNA methylation loci from two sets (c). The green and orange circles represent the set of DNA methylation loci associated with all PA variables (Set A) and all CVD variables (Set B), respectively. Heatmap (with M-value) shows the differential methylation level of the overlapped 23 loci in 1065 participants across PA quartiles and CVD status (d). Numbers beginning with “cg” are IlmnIDs

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BMC Genomics

ISSN: 1471-2164

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