LT | MV | |||||||
---|---|---|---|---|---|---|---|---|
ID | Description | ALL | UP | p | ALL | UP | p | |
Biological process | GO:0036159 | inner dynein arm assembly | 8 | 6 | 8.48 × 10−36 | 9 | 7 | 4.66 × 10−111 |
GO:0003341 | cilium movement | 25 | 9 | 6.19 × 10−34 | 16 | 8 | 4.36 × 10−98 | |
GO:0060271 | cilium morphogenesis | 53 | 10 | 5.85 × 10−22 | 29 | 5 | 2.38 × 10−25 | |
GO:0007018 | microtubule-based movement | 266 | 23 | 3.00 × 10−22 | 124 | 10 | 1.33 × 10− 26 | |
GO:0006974 | response to DNA damage stimulus | 47 | 5 | 1.84 × 10−06 | 35 | 5 | 1.50 × 10−21 | |
GO:0006355 | regulation of transcription, DNA-dependent | 724 | 18 | 6.60 × 10− 03 | 430 | 7 | 2.30 × 10− 03 | |
Molecular function | GO:0008569 | minus-end-directed microtubule motor activity | 21 | 9 | 1.15 × 10− 38 | 18 | 8 | 1.82 × 10−90 |
GO:0045503 | dynein light chain binding | 22 | 9 | 2.27 × 10−37 | 19 | 8 | 4.44 × 10−87 | |
GO:0051959 | dynein light intermediate chain binding | 23 | 9 | 3.74 × 10−36 | 20 | 8 | 6.21 × 10−84 | |
GO:0045505 | dynein intermediate chain binding | 27 | 9 | 5.80 × 10−32 | 22 | 8 | 2.85 × 10−78 | |
GO:0003777 | microtubule motor activity | 283 | 26 | 6.48 × 10−27 | 135 | 12 | 2.29 × 10−35 | |
GO:0005524 | ATP binding | 3724 | 122 | 1.77 × 10−24 | 1973 | 56 | 2.69 × 10−45 | |
GO:0008017 | microtubule binding | 236 | 20 | 5.43 × 10−19 | 147 | 5 | 1.32 × 10−05 | |
GO:0046872 | metal ion binding | 2030 | 53 | 6.82 × 10−07 | 1075 | 18 | 2.55 × 10− 07 | |
GO:0004842 | ubiquitin-protein ligase activity | 201 | 11 | 1.82 × 10−06 | 37 | 5 | 2.46 × 10− 09 | |
GO:0016887 | ATPase activity | 346 | 13 | 1.67 × 10−04 | 176 | 9 | 5.11 × 10−15 | |
GO:0031625 | ubiquitin protein ligase binding | 72 | 5 | 2.56 × 10− 04 | 87 | 5 | 1.59 × 10−20 | |
GO:0005509 | calcium ion binding | 737 | 20 | 1.22 × 10−03 | 394 | 11 | 2.72 × 10−09 | |
GO:0004674 | protein serine/threonine kinase activity | 324 | 11 | 1.82 × 10− 03 | 200 | 6 | 8.15 × 10−06 | |
Cellular component | GO:0005874 | microtubule | 265 | 36 | 2.17 × 10− 57 | 154 | 14 | 2.18 × 10−42 |
GO:0005929 | cilium | 33 | 12 | 2.88 × 10−46 | 31 | 12 | 2.54 × 10−127 | |
GO:0030286 | dynein complex | 108 | 15 | 1.40 × 10−24 | 42 | 9 | 1.82 × 10−58 | |
GO:0005737 | cytoplasm | 1719 | 72 | 1.04 × 10−23 | 1042 | 37 | 4.81 × 10−40 | |
GO:0016021 | integral to membrane | 8136 | 167 | 7.70 × 10−09 | 4727 | 60 | 3.49 × 10−13 | |
GO:0016020 | membrane | 520 | 21 | 2.39 × 10−07 | 336 | 14 | 1.34 × 10−18 | |
GO:0005634 | nucleus | 2937 | 65 | 2.97 × 10−05 | 1789 | 34 | 1.07 × 10−15 | |
GO:0005886 | plasma membrane | 843 | 25 | 5.15 × 10− 05 | 603 | 16 | 2.40 × 10−12 | |
GO:0005739 | mitochondrion | 419 | 12 | 7.14 × 10−03 | 285 | 8 | 5.31 × 10− 07 |