LT | MV | |||||||
---|---|---|---|---|---|---|---|---|
ID | Description | ALL | UP | p | ALL | UP | p | |
Biological process | GO:0006270 | DNA-dependent DNA replication initiation | 40 | 9 | 1.40 × 10−38 | 27 | 8 | 6.51 × 10−31 |
GO:0007155 | cell adhesion | 98 | 12 | 5.98 × 10− 30 | 83 | 13 | 2.82 × 10−29 | |
GO:0051056 | regulation of small GTPase med. Signal transduction | 38 | 7 | 7.97 × 10−25 | 26 | 5 | 4.58 × 10−13 | |
GO:0007616 | long-term memory | 22 | 5 | 1.68 × 10−20 | 23 | 5 | 1.79 × 10−14 | |
GO:0007229 | integrin-mediated signaling pathway | 76 | 8 | 4.48 × 10−17 | 67 | 6 | 7.39 × 10− 08 | |
GO:0007411 | axon guidance | 64 | 7 | 1.92 × 10−15 | 70 | 6 | 1.57 × 10−07 | |
GO:0007165 | signal transduction | 408 | 14 | 1.92 × 10−08 | 234 | 13 | 1.31 × 10−09 | |
GO:0006979 | response to oxidative stress | 109 | 6 | 9.48 × 10−07 | 76 | 7 | 2.27 × 10− 09 | |
GO:0035556 | intracellular signal transduction | 427 | 12 | 1.07 × 10−05 | 217 | 7 | 5.02 × 10−03 | |
GO:0016192 | vesicle-mediated transport | 159 | 6 | 1.43 × 10−04 | 114 | 5 | 2.60 × 10−3 | |
GO:0016567 | protein ubiquitination | 142 | 5 | 1.12 × 10−03 | 75 | 5 | 5.49 × 10−05 | |
GO:0007049 | cell cycle | 145 | 5 | 1.34 × 10−03 | 87 | 7 | 3.53 × 10−08 | |
GO:0006260 | DNA replication | 182 | 5 | 7.26 × 10− 03 | 74 | 7 | 1.27 × 10−09 | |
Molecular function | GO:0005096 | GTPase activator activity | 183 | 14 | 1.19 × 10−21 | 112 | 12 | 1.58 × 10−18 |
GO:0003678 | DNA helicase activity | 76 | 8 | 4.48 × 10−17 | 55 | 7 | 8.04 × 10−13 | |
GO:0051015 | actin filament binding | 120 | 10 | 5.96 × 10− 17 | 70 | 7 | 3.65 × 10−10 | |
GO:0046872 | metal ion binding | 2030 | 50 | 3.13 × 10−16 | 1075 | 34 | 4.23 × 10− 10 | |
GO:0005524 | ATP binding | 3724 | 70 | 3.80 × 10− 13 | 1973 | 48 | 3.15 × 10−08 | |
GO:0003779 | actin binding | 234 | 11 | 5.71 × 10− 10 | 147 | 14 | 4.72 × 10−19 | |
GO:0005200 | structural constituent of cytoskeleton | 56 | 5 | 4.92 × 10−09 | 31 | 6 | 5.92 × 10− 16 | |
GO:0005525 | GTP binding | 581 | 16 | 4.92 × 10−07 | 331 | 11 | 2.49 × 10− 03 | |
GO:0003700 | sequence-specific DNA bind. Transcr. factor activity | 605 | 17 | 1.27 × 10− 07 | 335 | 9 | 7.62 × 10− 03 | |
GO:0003723 | RNA binding | 1017 | 22 | 2.51 × 10−06 | 545 | 18 | 2.57 × 10− 06 | |
GO:0042802 | identical protein binding | 123 | 6 | 5.74 × 10− 06 | 87 | 6 | 4.55 × 10− 06 | |
GO:0005509 | calcium ion binding | 737 | 17 | 1.07 × 10−05 | 394 | 14 | 9.96 × 10− 06 | |
GO:0003924 | GTPase activity | 426 | 11 | 9.50 × 10− 05 | 249 | 10 | 3.91 × 10− 05 | |
GO:0004930 | G-protein coupled receptor activity | 258 | 7 | 1.37 × 10−03 | 159 | 10 | 9.57 × 10− 09 | |
GO:0003677 | DNA binding | 2066 | 29 | 2.17 × 10− 03 | 1362 | 25 | 8.86 × 10− 03 | |
GO:0008017 | microtubule binding | 236 | 6 | 5.41 × 10− 03 | 147 | 7 | 1.07 × 10− 03 | |
Cellular component | GO:0042555 | MCM complex | 29 | 8 | 3.05 × 10− 40 | 18 | 8 | 5.19 × 10− 42 |
GO:0031594 | neuromuscular junction | 14 | 5 | 3.98 × 10− 29 | 16 | 6 | 4.09 × 10− 27 | |
GO:0005886 | plasma membrane | 843 | 35 | 1.63 × 10− 25 | 603 | 41 | 7.88 × 10− 37 | |
GO:0005737 | cytoplasm | 1719 | 47 | 2.89 × 10−18 | 1042 | 44 | 1.91 × 10−20 | |
GO:0005925 | focal adhesion | 89 | 8 | 1.25 × 10− 14 | 34 | 7 | 8.30 × 10− 20 | |
GO:0005634 | nucleus | 2937 | 54 | 6.24 × 10− 10 | 1789 | 48 | 4.47 × 10− 10 | |
GO:0031012 | extracellular matrix | 76 | 6 | 1.18 × 10− 09 | 40 | 5 | 5.72 × 10− 09 | |
GO:0016021 | integral to membrane | 8136 | 107 | 1.68 × 10− 07 | 4727 | 125 | 8.67 × 10− 24 | |
GO:0000139 | Golgi membrane | 177 | 8 | 3.97 × 10− 07 | 112 | 5 | 2.27 × 10− 03 | |
GO:0005887 | integral to plasma membrane | 164 | 7 | 6.04 × 10− 06 | 122 | 8 | 1.79 × 10− 07 | |
GO:0016020 | membrane | 520 | 13 | 3.52 × 10− 05 | 336 | 14 | 4.05 × 10− 07 | |
GO:0005829 | cytosol | 788 | 17 | 3.90 × 10− 05 | 620 | 22 | 2.45 × 10− 08 | |
GO:0005622 | intracellular | 1029 | 19 | 2.52 × 10− 04 | 512 | 16 | 2.75 × 10− 05 | |
GO:0005576 | extracellular region | 380 | 9 | 1.18 × 10− 03 | 273 | 8 | 6.03 × 10–03 | |
GO:0005856 | cytoskeleton | 154 | 5 | 2.18 × 10− 03 | 99 | 6 | 2.53 × 10− 05 | |
GO:0005874 | microtubule | 265 | 6 | 1.22 × 10− 02 | 154 | 6 | 2.37 × 10− 03 |