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Table 3 Most significant (p < 0.05) GO terms enriched in haemolymph of both LT and MV. ALL = count number of all GO retrieved in transcriptome; UP = count number of enriched GO

From: Unraveling the role of male reproductive tract and haemolymph in cantharidin-exuding Lydus trimaculatus and Mylabris variabilis (Coleoptera: Meloidae): a comparative transcriptomics approach

   

LT

MV

 

ID

Description

ALL

UP

p

ALL

UP

p

Biological process

GO:0006270

DNA-dependent DNA replication initiation

40

9

1.40 × 10−38

27

8

6.51 × 10−31

GO:0007155

cell adhesion

98

12

5.98 × 10− 30

83

13

2.82 × 10−29

GO:0051056

regulation of small GTPase med. Signal transduction

38

7

7.97 × 10−25

26

5

4.58 × 10−13

GO:0007616

long-term memory

22

5

1.68 × 10−20

23

5

1.79 × 10−14

GO:0007229

integrin-mediated signaling pathway

76

8

4.48 × 10−17

67

6

7.39 × 10− 08

GO:0007411

axon guidance

64

7

1.92 × 10−15

70

6

1.57 × 10−07

GO:0007165

signal transduction

408

14

1.92 × 10−08

234

13

1.31 × 10−09

GO:0006979

response to oxidative stress

109

6

9.48 × 10−07

76

7

2.27 × 10− 09

GO:0035556

intracellular signal transduction

427

12

1.07 × 10−05

217

7

5.02 × 10−03

GO:0016192

vesicle-mediated transport

159

6

1.43 × 10−04

114

5

2.60 × 10−3

GO:0016567

protein ubiquitination

142

5

1.12 × 10−03

75

5

5.49 × 10−05

GO:0007049

cell cycle

145

5

1.34 × 10−03

87

7

3.53 × 10−08

GO:0006260

DNA replication

182

5

7.26 × 10− 03

74

7

1.27 × 10−09

Molecular function

GO:0005096

GTPase activator activity

183

14

1.19 × 10−21

112

12

1.58 × 10−18

GO:0003678

DNA helicase activity

76

8

4.48 × 10−17

55

7

8.04 × 10−13

GO:0051015

actin filament binding

120

10

5.96 × 10− 17

70

7

3.65 × 10−10

GO:0046872

metal ion binding

2030

50

3.13 × 10−16

1075

34

4.23 × 10− 10

GO:0005524

ATP binding

3724

70

3.80 × 10− 13

1973

48

3.15 × 10−08

GO:0003779

actin binding

234

11

5.71 × 10− 10

147

14

4.72 × 10−19

GO:0005200

structural constituent of cytoskeleton

56

5

4.92 × 10−09

31

6

5.92 × 10− 16

GO:0005525

GTP binding

581

16

4.92 × 10−07

331

11

2.49 × 10− 03

GO:0003700

sequence-specific DNA bind. Transcr. factor activity

605

17

1.27 × 10− 07

335

9

7.62 × 10− 03

GO:0003723

RNA binding

1017

22

2.51 × 10−06

545

18

2.57 × 10− 06

GO:0042802

identical protein binding

123

6

5.74 × 10− 06

87

6

4.55 × 10− 06

GO:0005509

calcium ion binding

737

17

1.07 × 10−05

394

14

9.96 × 10− 06

GO:0003924

GTPase activity

426

11

9.50 × 10− 05

249

10

3.91 × 10− 05

GO:0004930

G-protein coupled receptor activity

258

7

1.37 × 10−03

159

10

9.57 × 10− 09

GO:0003677

DNA binding

2066

29

2.17 × 10− 03

1362

25

8.86 × 10− 03

GO:0008017

microtubule binding

236

6

5.41 × 10− 03

147

7

1.07 × 10− 03

Cellular component

GO:0042555

MCM complex

29

8

3.05 × 10− 40

18

8

5.19 × 10− 42

GO:0031594

neuromuscular junction

14

5

3.98 × 10− 29

16

6

4.09 × 10− 27

GO:0005886

plasma membrane

843

35

1.63 × 10− 25

603

41

7.88 × 10− 37

GO:0005737

cytoplasm

1719

47

2.89 × 10−18

1042

44

1.91 × 10−20

GO:0005925

focal adhesion

89

8

1.25 × 10− 14

34

7

8.30 × 10− 20

GO:0005634

nucleus

2937

54

6.24 × 10− 10

1789

48

4.47 × 10− 10

GO:0031012

extracellular matrix

76

6

1.18 × 10− 09

40

5

5.72 × 10− 09

GO:0016021

integral to membrane

8136

107

1.68 × 10− 07

4727

125

8.67 × 10− 24

GO:0000139

Golgi membrane

177

8

3.97 × 10− 07

112

5

2.27 × 10− 03

GO:0005887

integral to plasma membrane

164

7

6.04 × 10− 06

122

8

1.79 × 10− 07

GO:0016020

membrane

520

13

3.52 × 10− 05

336

14

4.05 × 10− 07

GO:0005829

cytosol

788

17

3.90 × 10− 05

620

22

2.45 × 10− 08

GO:0005622

intracellular

1029

19

2.52 × 10− 04

512

16

2.75 × 10− 05

GO:0005576

extracellular region

380

9

1.18 × 10− 03

273

8

6.03 × 10–03

GO:0005856

cytoskeleton

154

5

2.18 × 10− 03

99

6

2.53 × 10− 05

GO:0005874

microtubule

265

6

1.22 × 10− 02

154

6

2.37 × 10− 03