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Fig. 6 | BMC Genomics

Fig. 6

From: CoRe: a robustly benchmarked R package for identifying core-fitness genes in genome-wide pooled CRISPR-Cas9 screens

Fig. 6

Functional characterisation of predicted core-fitness/common-essential genes. A. Gene families consistently significantly enriched (FDR < 5%) across all the state-of-the-art set of core-fitness essential genes (CFGs) and those outputted by the supervised methods. B. Gene families consistently and significantly enriched (FDR < 5%) across all the common-essential gene (CEG) sets outputted by the CoRe FiPer variants. C Percentage of early and mid/late essential gene families that are also always enriched across CFG and CEG sets or in CEG sets only

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