Fig. 5
From: Identification and functional analysis of novel oncogene DDX60L in pancreatic ductal adenocarcinoma
Knockdown of DDX60L induced apoptosis of PDAC cells, but not cell cycle arrest. (A, B) Apoptosis of siRNA-transfected PDAC cells. FACS analyzed the apoptosis of the siControl-, siMYEOV-, and siDDX60L-transfected PANC-1 (A) and MiaPaca2 (B) cells. (C, D) Cell cycle of siRNA-transfected PDAC cells. FACS analyzed the cell cycle of the siControl-, siMYEOV-, and siDDX60L-transfected PANC-1 (C) and MiaPaca2 (D) cells. One-way ANOVA is used to analyze significant differences. Ns, no significant differences, *p < 0.05; **p < 0.01; ***p < 0.001. DDX60L, DExD/H-box 60 like; FACS, fluorescence-activated cell sorting; MYEOV, myeloma overexpressed; PDAC, pancreatic ductal adenocarcinoma