Fig. 4

eQTL and ASE analyses of IMF-correlated genes. (A). Veen diagram of significantly cis-eQTL target genes, ASE genes and IMF-correlated genes. (B). Veen diagram of significantly specific trans-eQTL target genes and IMF-correlated genes. (C). The Manhattan plot of NAXE. The red dashed line represents the cutoff of statistical significance at the genome-wide level (p = 0.05/36045). (D). Boxplot of the allele-specific expression ratio of NAXE for the SNP of rs326817713 (G > T). Allele-specific expression ratio means the number of reads aligned to the reference allele divided by the total number of reads aligned to this site. “ASE sample” (red dot) indicates the heterozygotes with ASE signal at this site, and “Non-ASE sample” (green dot) indicates the heterozygotes without ASE signal at this site. (E). Boxplot of the expression level of NAXE with different genotypes of rs326817713. (F). The Manhattan plot of PARK7. The red dashed line represents the cutoff of statistical significance at the genome-wide level (p = 0.05/36,045)