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Table 1 IRF8 target gene regulation prediction based on the regulation prediction using SVM, NN and log2FC only

From: Predicting the targets of IRF8 and NFATc1 during osteoclast differentiation using the machine learning method framework cTAP

Model Up regulation Down regulation
Log2FC only AIF1, CD164, MARCKS, MEF2C, RNASE4, TLR6, LSP1 NDUFS7, RAB3IP, NUDT13, MCRS1, COX15, ATP5L
SVM AIF1, BID, CASP1, CTPS2, H2-M3, IRF5, LSP1, SLC15A3, TLR6 NDUFS7, PARP8, NUDT13, MCRS1, COX15, ATP5L, ALG9
NN AIF1, BID, CTPS2, MARCKS, RNASE4, H2-M3, SLC15A3, NOTCH1, LSP1 NDUFS7, RAB3IP, NUDT13, MCRS1, TAP2, COX15, ATP5L
Gaussian NB ATP6V0A1, CCL6, CCRL2, FGD2, LSP1, LY86, NOTCH1, P2RY12, PLSCR3, RNASE4, SLA, SLC15A3, STAT2, TNFRSF13B, TRIM21 GTF3C5, RAB3IP
LR AIF1, CTPS2, H2-M3, MARCKS, NOTCH1, RNASE4, S100A13, SLC15A3, TLR6, TNFRSF1B ATP5L, NDUFS7