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Table 1 IRF8 target gene regulation prediction based on the regulation prediction using SVM, NN and log2FC only

From: Predicting the targets of IRF8 and NFATc1 during osteoclast differentiation using the machine learning method framework cTAP

Model

Up regulation

Down regulation

Log2FC only

AIF1, CD164, MARCKS, MEF2C, RNASE4, TLR6, LSP1

NDUFS7, RAB3IP, NUDT13, MCRS1, COX15, ATP5L

SVM

AIF1, BID, CASP1, CTPS2, H2-M3, IRF5, LSP1, SLC15A3, TLR6

NDUFS7, PARP8, NUDT13, MCRS1, COX15, ATP5L, ALG9

NN

AIF1, BID, CTPS2, MARCKS, RNASE4, H2-M3, SLC15A3, NOTCH1, LSP1

NDUFS7, RAB3IP, NUDT13, MCRS1, TAP2, COX15, ATP5L

Gaussian NB

ATP6V0A1, CCL6, CCRL2, FGD2, LSP1, LY86, NOTCH1, P2RY12, PLSCR3, RNASE4, SLA, SLC15A3, STAT2, TNFRSF13B, TRIM21

GTF3C5, RAB3IP

LR

AIF1, CTPS2, H2-M3, MARCKS, NOTCH1, RNASE4, S100A13, SLC15A3, TLR6, TNFRSF1B

ATP5L, NDUFS7