Table 1 Norepinephrine enhanced expression of genes encoding virulence pathways

Virulence/LEE

BHW77_00345

sepD

lytic transglycosylase

+ 2.04

2.06E-02

BHW77_00350

escJ

Secreted inner membrane

ring protein

+ 2.25

1.29E-02

BHW77_00355

escI

Type III secretion system (T3SS)

inner rod protein

+ 3.04

5.54E-06

BHW77_00360

sepZ

T3SS protein

+ 2.80

1.58E-06

BHW77_00365

cesL

T3SS regulator

+ 3.12

2.43E-06

BHW77_00370

escV

T3SS export apparatus protein

+ 2.29

1.56E-04

BHW77_00400

cesF

T3SS molecular chaperone

+ 3.12

1.31E-06

BHW77_00405

map

T3SS effector protein

+ 3.88

3.24E-11

BHW77_00430

sepL

T3SS gatekeeper

+ 4.49

1.52E-08

BHW77_00435

espA

T3SS needle protein

+3.236

9.67E-05

BHW77_00440

espD

T3SS needle protein

+2.995

6.62E-05

BHW77_00445

espB

T3SS translocon pore-forming subunit

+ 3.15

6.19E-06

BHW77_00450

cesD

T3SS chaperon

+ 3.06

1.12E-06

Virulence/stx2

BHW77_10375

stx2A

Shiga toxin subunit A

+ 4.08

4.66E-10

BHW77_10380

stx2B

Shiga toxin subunit B

+ 3.37

2.09E-09

Virulence/LEE, stx transcriptional regulators

BHW77_09855

perC

PerC family protein transcriptional regulator

+ 2.47

3.28E-04

BHW77_18290

perC

PerC family protein transcriptional regulator

+ 2.57

1.23E-03

Virulence/Fimbriae

BHW77_01085

lpfB

long polar fimbrial chaperone LpfB

+ 2.45

1.00E-04

BHW77_01095

lpfD

fimbrial family protein

+ 3.01

1.43E-06

BHW77_20140

ybgP

fimbrial protein

+ 2.02

7.68E-04

BHW77_11425

csgB

curli subunit protein

+ 7.85

3.20E-02