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Fig. 4 | BMC Genomics

Fig. 4

From: N7-methylguanosine modification of lncRNAs in a rat model of hypoxic pulmonary hypertension: a comprehensive analysis

Fig. 4

Identification of differentially expressed lncRNAs in lungs of HPH rats compared to normobaric normoxic rats. a Heatmap of RNA sequencing data from the two groups. Red, green and black indicate up-regulation, unchanged expression and down-regulation of lncRNAs, respectively. b Scatterplot of RNA sequencing data. GO enrichment analysis of genes located near (c) up-regulated and (d) down-regulated lncRNAs. GO enrichment analysis included BP, CC and MF analysis. KEGG pathway analysis of genes located near (e) up-regulated and (f) down-regulated lncRNAs. P-values were calculated using DAVID. Selection Counts indicate the number of selected genes that overlap with differentially methylated lncRNAs in that pathway. n = 3 for each group

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