Fig. 7

Species-specific mutation enrichment among aminoacyl-tRNA synthetase domains relative to corresponding full proteins. a Enrichment of aminoacyl-tRNA synthetase (AARS) related features among all domains with significant mutation enrichment or depletion. b Extent of mutation enrichment in AARS domains compared to function across 12 species. Each point corresponds to a single gene-domain pair, categorized by function based on InterPro descriptions. c Species-specific mutation enrichment for all AARS-associated gene-domain pairs, sorted by domain entropy percentile averaged across the 12 species. White cells correspond to domains that could not be annotated within the species’ consensus sequence of the parent protein