Fig. 2

Temporal activity and gene and protein expression supports extreme physiological shifts. a Differentially expressed genes and cluster into discrete patterns with specific GO Term functional enrichment throughout the time series. b Heatmap of average protein quantitation, scaled by row and hierarchically clustered. Line plots reproduce patterns of protein expression in each cluster. c Top five enrichment terms for GO biological process (clusters 1 and 3) or KEGG pathways (clusters 2, 4, and 5) for proteins in each cluster. d Summary of major enriched functions aligned with peaks in measured physiological changes throughout the time series