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Fig. 5 | BMC Genomics

Fig. 5

From: A novel graph-based k-partitioning approach improves the detection of gene-gene correlations by single-cell RNA sequencing

Fig. 5

Evaluations of scCorr performance in gene-gene correlations in wild-type and knockout cells in dataset 2. In wild-type cells, the nonclustering single-cell correlation method showed no significant correlation between MAP7D1 and MAN2A1 (r < 0.001; p = 0.624) (A), while cluster-based scCorr showed a significant correlation between the two genes (r = 0.785; p = 1.80E-34) (B). In knockout cells, the nonclustering single-cell correlation method showed no significant correlation between LASP1 and KLF13 (r < 0.001; p = 0.100) (C), while cluster-based scCorr showed a significant correlation between the two genes (r = 0.722; p = 5.36E-29) (D)

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