Fig. 10

Additional examples of 5hmC vs CpG 5mC for representative genes changing in expression during ONC. Track labels, as well as red, green, and blue boxes, are as in Fig. 10. Magenta boxes, examples of increased H3K27ac marks induced by ONC. All genes exhibited the same behavior with respect to CpG as illustrated previously for ezh2.L, vim.L, idh1.L and jarid2.S in tadpole hindbrain after SCI (Fig. 3). Changes in 5hmC (Δ5hmC ONC: olive green, up; blue green, down) across the TSS were generally not congruent with those of CpG 5mC marks (blue boxes vs. green boxes, respectively). Blue ellipse, vim.L, an integrated adenoviral sequence marked by 5hmC