Table 2 Frequencies for ILA, ILB, and ILRN genotypes in OVER, CON, and ALL groups, probabilities that the genotype frequencies do not differ from Hardy-Weinberg expectations (HWE) and minor allele frequency (MAF)
From: The interactions between interleukin-1 family genes: IL1A, IL1B, IL1RN, and obesity parameters
SNP | Genotype | OVER N (%) | HWE p-value | CON N (%) | HWE p-value | ALL N (%) | HWE p-value | MAF (%) |
|---|---|---|---|---|---|---|---|---|
BMI groups | ||||||||
IL1A rs1800587 | C/C | 16 (64) | 0.55 | 40 (52.6) | 0.01 | 56 (55.4) | 0.003 | Allele T (22.3) |
T/C | 9 (36) | 36 (47.4) | 45 (44.6) | |||||
T/T | 0 (0) | 0 (0) | 0 (0) | |||||
IL1B rs1143634 | C/C | 11 (44) | 1 | 40 (52.6) | 0.56 | 51 (50.5) | 0.81 | Allele T (28.2) |
T/C | 11 (44) | 32 (42.1) | 43 (42.6) | |||||
T/T | 3 (12) | 4 (5.3) | 7 (6.9) | |||||
IL1RN rs2234677 | G/G | 17 (68) | 1 | 35 (46.0) | 0.28 | 52 (51.5) | 0.32 | Allele A (26.7) |
A/G | 7 (28) | 37 (48.7) | 44 (43.6) | |||||
A/A | 1 (4) | 4 (5.3) | 5 (4.9) | |||||
Fat % groups | ||||||||
IL1A rs1800587 | C/C | 9 (64.3) | 1 | 47 (54.0) | 0.01 | 56 (55.5) | 0.003 | Allele T (22.3) |
T/C | 5 (35.7) | 40 (46.0) | 45 (44.5) | |||||
T/T | 0 (0) | 0 (0) | 0 (0) | |||||
IL1B rs1143634 | C/C | 7 (50.0) | 0.55 | 44 (50.6) | 0.59 | 51 (50.5) | 0.81 | Allele T (28.2) |
T/C | 5 (35.7) | 38 (43.7) | 43 (42.6) | |||||
T/T | 2 (14.3) | 5 (5.7) | 7 (6.9) | |||||
IL1RN rs2234677 | G/G | 10 (71.4) | 0.35 | 42 (48.3) | 0.19 | 52 (51.5) | 0.32 | Allele A (26.7) |
A/G | 3 (21.5) | 41 (47.1) | 44 (43.5) | |||||
A/A | 1 (7.1) | 4 (5.60) | 5 (5.0) | |||||