Table 5 Analysis of the IL1B(rs1143634) x IL1RN (rs2234677) interaction in relation to fat % (codominant model. OR—odds ratio, CI—confidence intervals, NA—not applicable
From: The interactions between interleukin-1 family genes: IL1A, IL1B, IL1RN, and obesity parameters
IL1RN (rs2234677) | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Codominant model | |||||||||||||||||
IL1B (rs1143634) | G/G | A/G | A/A | ||||||||||||||
OVERFat | CONFat | OR | 95% CI | OVERFat | CONFat | OR | 95% CI | OVERFat | CONFat | OR | 95% CI | p | |||||
C/C | 6 | 19 | 1.00 | NA | NA | 4 | 19 | 0.67 | 0.16 | 2.75 | 0 | 4 | 0.00 | 0.00 | NA | 0.01 | |
T/C | 1 | 24 | 0.13 | 0.01 | 1.19 | 0 | 16 | 0.00 | 0.00 | NA | 2 | 1 | 6.33 | 0.48 | 82.75 | ||
T/T | 0 | 1 | 0.00 | 0.00 | NA | 1 | 3 | 1.06 | 0.09 | 12.14 | 0 | 0 | NA | NA | NA | ||
Recessive model | |||||||||||||||||
G/G-A/G | A/A | ||||||||||||||||
OVERFat | CONFat | OR | 95% CI | OVERFat | CONFat | OR | 95% CI | p | |||||||||
C/C | 10 | 38 | 1.00 | NA | NA | 0 | 4 | 0.00 | 0.00 | NA | 0.002 | ||||||
T/C | 1 | 40 | 0.10 | 0.01 | 0.78 | 2 | 1 | 7.60 | 0.62 | 92.54 | |||||||
T/T | 1 | 4 | 0.95 | 0.10 | 9.47 | 0 | 0 | NA | NA | NA | |||||||