Fig. 1

(Left) Precision-recall curves of our method using the D. melanogaster proteome reference and the Bowtie2-RSEM-DESeq2 pipeline using its transcriptome reference. The three shape markers in each curve correspond to setting the FDR threshold of DESeq2 to 0.01, 0.05, and 0.1. (Right) Log fold change of true positive DE genes estimated by DESeq2 at FDR threshold of 0.1, compared against the 6 simulated log-fold change levels