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Table 2 Estimated type I error rates for the rare variant mixed model methods implemented in SMMAT

From: Comparison of mixed model based approaches for correcting for population substructure with application to extreme phenotype sampling

SMMAT Method

Estimated Type I Error Rate

Burden (SMMAT-B)

0.0617

SKAT (SMMAT-S)

0.1039

SKAT-O (SMMAT-O)

0.1024

Efficient (SMMAT-E)

0.0883