Table 2 The number of gene copies that OGs expanded /contracted in N. pumilus than the last common ancestor of ladybirds

Papain family cysteine protease

+ 10

0.0293442

PF00112

(130) 25

−81,374.615334

−81,370.385291

Model A vs. Model A null

8.460086

0.003630247^*

GIY-YIG catalytic domain

+ 10

0.0115812

PF01541

(77) 20

−63,449.8

−63,449.8

Model A vs. Model A null

2.00E-06

0.997743

Zinc finger, C2H2 type

+ 65

2.6335E-23

PF00096

(78) 71

−76,378.4

−76,373.7

Model A vs. Model A null

9.333846

0.002249597^*

Papain family cysteine protease

+ 11

0.00067968

PF00112

(62) 16

−42,889.4

−42,889.1

Model A vs. Model A null

0.437724

0.508223

Bacterial extracellular solute-binding proteins, family 3

+ 55

6.5167E-21

PF00497

(60) 59

−65,378.7

−65,372.3

Model A vs. Model A null

12.70093

0.000365475^**

Histidine phosphatase superfamily (branch 2)

+ 9

0.00432895

PF00328

(59) 15

−50,522.7

−50,522.7

Model A vs. Model A null

0

1

Retroviral aspartyl protease

+ 49

2.2232E-19

PF00077

52

31,763.07136

31,763.07136

M1a vs. M2a

0

1

YqaJ-like viral recombinase domain

+ 6

0.0286801

PF09588

(46) 11

−20,486.4

−20,481.5

Model A vs. Model A null

9.742052

0.001800997^*

CRAL/TRIO domain

+ 10

0.00223833

PF00650

(47) 16

−32,465.4

−32,462.9

Model A vs. Model A null

5.072066

0.024314388^*

unknown

+ 43

5.7991E-17

unknown

46

−39,594.10792

−39,394.06476

M1a vs. M2a

400.0863

0^**

7tm Odorant receptor

+ 14

3.346E-05

PF02949

(39) 18

−28,871.9

−28,867.7

Model A vs. Model A null

8.308994

0.003944924^*

Leucine rich repeat

+ 36

4.71E-15

PF13855

38

31,494.14597

31,494.14597

M1a vs. M2a

0

1

unknown

+ 34

3.0939E-14

unknown

36

− 3339.182609

− 3330.176841

M1a vs. M2a

18.01154

0.0001227^*

Integrase core domain

+ 6

0.0286801

PF00665

(35) 11

−22,990.3

−22,990.3

Model A vs. Model A null

0

1

unknown

+ 22

2.2991E-09

unknown

(25) 24

− 8370.951276

− 8369.324548

Model A vs. Model A null

3.253456

0.071273

Domain of unknown function (DUF4769)

+ 3

0.0234649

PF15992

(23) 4

−11,711

− 11,707.8

Model A vs. Model A null

6.345562

0.011767532^*

Gamma interferon inducible lysosomal thiol reductase (GILT)

+ 18

1.1647E-08

PF03227

19

− 8954.59711

− 8930.826609

M1a vs. M2a

47.541

0^**

Core histone H2A/H2B/H3/H4

−5

0.0475987

PF00125

(89) 1

− 8236.68

− 8196.31

Model A vs. Model A null

−80.7418

0^**

Baculovirus FP protein

−6

0.00719925

PF03258

(87) 0

−44,251.4

−44,246.9

Model A vs. Model A null

−8.99553

0.002706408^*

Matrixin

−4

0.047769

PF00413

(80) 0

−34,306.30303

−34,295.78115

Model A vs. Model A null

21.04375

0.000004489^*

Core histone H2A/H2B/H3/H4

−5

0.0475987

PF00125

(77) 1

− 9959.15

− 9959.15

Model A vs. Model A null

2.00E-06

0.998872

unknown

−5

0.0183516

unknown

(73) 0

−27,707.9

− 27,682.2

Model A vs. Model A null

51.30864

0^**

Core histone H2A/H2B/H3/H4

−4

0.047769

PF00125

(66) 0

− 4648.924631

− 4617.070009

Model A vs. Model A null

63.7092439999997

0^**

DDE superfamily endonuclease

−4

0.047769

PF13359

(58)0

−17,817.03628

−17,815.55146

M1a vs. M2a

2.96964

0.226543

RNase H

−4

0.047769

PF00075

(51) 0

−38,944.3

−38,937.9

Model A vs. Model A null

12.86602

0.000334602^**

Retrotransposon gag protein

−4

0.047769

PF03732

(49) 0

−16,647

−16,636.2

Model A vs. Model A null

21.48437

0.000003567^**

unknown

−4

0.047769

unknown

(46) 0

−10,117.57741

−10,103.67858

M1a vs. M2a

27.79766

0^**

Transposase protein

−4

0.047769

PF12017

(44) 0

−28,053

−28,048.2

Model A vs. Model A null

9.461622

0.002098155^*

Cysteine-rich secretory protein family

−4

0.047769

PF00188

(34) 0

−50,366.08197

−50,366.08197

Model A vs. Model A null

0

1