Fig. 5

Genome-wide determination of transcription units. a The number of determined TUs from TSSs and TEPs. The determined TUs were classified as either mono-cistronic, poly-cistronic, cis-regulatory, or small RNA TU based on the number of associated genes or the distance from TSS to downstream gene. The identified cis-regulatory TUs or small RNA TUs were searched against the Rfam database. b Examples of TU types identified in this study. c Functional relatedness of genes belonging to same poly-cistronic TU. The functional enrichment was defined as the maximum frequency of genes with same COG functional category in a single poly-cistronic TU. *P-value < 0.001 (Wilcoxon rank sum test, two-sided) (d) Number of genes within a TU containing a certain gene in a secondary metabolite biosynthesis gene cluster. C, A, R, and T represent core, additional, regulatory, and transport related gene containing TU, respectively. *P-value < 0.05 (Wilcoxon rank sum test, two-sided) (e) The number of TU clusters containing certain number of genes. f The number of TU in a TU cluster