Table 2 CNV information and pregnancy outcome of CNVs grouped by parent-of-origin
Group | Number of samples, n (%) | Overlap of HI, n (%) | Average size of CNV(Mb) | Outcome of pregnancy, n (%) | ||
|---|---|---|---|---|---|---|
Normal infants | Abnormal pregnancy outcomes | Voluntary TOP | ||||
Detection of parent-of-origin | 82 (61.2%) | 25 (30.5%) | 1.07 | 62 (75.6%) | 7 (8.5%) | 13 (15.9%) |
Inherited | 60 (73.2%) | 15 (25.0%) | 0.81 | 55 (91.7%) | 4 (6.7%) | 1 (1.7%) |
De novo | 22 (26.8%) | 10 (45.5%) | 1.77 | 7 (31.8%) | 3 (13.6%) | 12 (54.5%) |
Unknown origin | 52 (38.8%) | 16 (30.8%) | 1.18 | 42 (80.8%) | 6 (11.5%) | 4 (7.7%) |
Total | 134 (100.0%) | 41 (30.6%) | 1.11 | 104 (77.6%) | 13 (9.7%) | 17 (12.7%) |