Fig. 4

Prophage synteny analysis. The two most outer layers represent both functional annotations derived from the COGs database and NCBP-PGAP. Number of genes with either known (dark blue) or unknown (light blue) annotations are also shown in brackets. The genomes of Brachyspira hyodysenteriae strains that share some of the phage-like genes found in the novel prophage of B. hyodysenteriae isolate Bh743-7 (in orange) are represented by the black inner layers. Although the novel prophage was not present in any of the analysed strains, homologous genes were found in those strains by forcing synteny as highlighted. In the centre, a zoom in barcode-like graph is showing the presence (black) /absence (white) of the homologous genes. Total number of singletons per genome is also indicated in the bar graph