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Fig. 1 | BMC Genomics

Fig. 1

From: MutationalPatterns: the one stop shop for the analysis of mutational processes

Fig. 1

Mutation profiles can be made for multiple mutation types. a Relative contribution of the indicated mutation types to the point mutation spectrum. Bars depict the mean relative contribution of each mutation type over all the samples and error bars indicate the 95% confidence interval. The dots show the relative contributions of the individual samples. The total number of somatic point mutations per tissue is indicated. b Absolute contribution of the indicated mutation types to the indel spectrum for the wild-type (WT) and MSH2 knockout. The total number of indels per sample is indicated. c Absolute contribution of the indicated mutation types to the DBS spectrum for the wild-type (WT) and XPC knockout. The total number of DBSs per sample is indicated. d Heatmap depicting the relative contribution of the indicated mutation types and the surrounding bases to the point mutation spectrum for the WT and MSH2 knockout. The total number of somatic point mutations per tissue is indicated

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