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Table 3 List of Khib proteins involved in sterol biosynthesis in F. graminearum

From: Quantitative multiplexed proteomics analysis reveals reshaping of the lysine 2-hydroxyisobutyrylome in Fusarium graminearum by tebuconazole

Gene locus

Protein accession

Gene function

Number of Khib sites

Number of changed Khib sitesa

Khib proteins involved in terpenoid backbone biosynthesis (fgr00900)

 FGSG_10424

I1S130

MVD, ERG19, diphosphomevalonate decarboxylase [EC:4.1.1.33]

2

1 up

 FGSG_09722

I1RZ92

IDI; isopentenyl-diphosphate delta-isomerase [EC:5.3.3.2]

4

1 up

 FGSG_06784

V6RG22

FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]

9

5 up

 FGSG_05911

A0A098E2N1

FNTA; protein Farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha [EC:2.5.1.58 2.5.1.59]

1

0

Khib proteins involved in steroid biosynthesis

 FGSG_09381

V6RPN0

FDFT1, ERG9; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]

2

1 up

 FGSG_04092

I1RJR2

CYP51A; sterol 14-demethylase [EC:1.14.13.70]

1

0

 FGSG_01000

I1RBR4

CYP51B; sterol 14-demethylase [EC:1.14.13.70]

6

1 down

 FGSG_01203

I1RCA0

NSDHL, ERG26; sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) [EC:1.1.1.170]

2

0

 FGRAMPH1_

01T26961

A0A1C3YLL7

ERG27; 3-keto steroid reductase [EC:1.1.1.270]

1

0

 FGSG_05740

A0A0E0SMA3

SMT1A, ERG6A; sterol 24-C-methyltransferase [EC:2.1.1.41]

1

0

 FGSG_02783

I1RGC4

SMT1B, ERG6B; sterol 24-C-methyltransferase [EC:2.1.1.41]

1

1 down

 FGSG_07315

I1RT23

ERG2; C-8 sterol isomerase [EC:5.-.-.-]

2

0

  1. a Number of Khib sites which influenced by TEC