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Table 5 The frameshift substitution scores of the natural and alternative genetic codes

From: Frameshift and wild-type proteins are often highly similar because the genetic code and genomes were optimized for frameshift tolerance

Genetic codes (Number tested)

Scoring Matrix

FSS of the natural genetic code (NGC)

FSS of the alternative genetic codes

FSS Score

Rank

Rank%

STDEV

STDEV%

Average

STDEV

STDEV%

Random (1,000,000 × 100)

PAM250

− 344

132,586.79

13.26%

1011.17

0.1011%

− 504.88

0.54

−0.1073%

Blossum62

− 276

19,752.52

1.98%

295.17

0.0295%

−450.53

0.27

−0.0598%

Gonnet250

−912

29,447.26

2.94%

398.72

0.0399%

− 2872.95

4.16

−0.1447%

Compatible (13824)

PAM250

−344

4273

30.91%

–

–

−401.25

–

–

Blossum62

−276

481

3.48%

–

–

−436.75

–

–

Gonnet250

−912

481

3.48%

–

–

− 2736.13

–

–