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Table 5 Summary of Ingenuity Pathway Analysis results for C2 and SR comparison

From: Transcriptome analysis of blastoderms exposed to prolonged egg storage and short periods of incubation during egg storage

Network Score

Functions

42

Carbohydrate Metabolism, Energy Production

Regulators in Network

Score

Targets

Functions

MACROH2A1

3

4

Consumption of D-glucose, Binding of lipid, Binding of palmitoyl-coenzyme A

Upstream Regulator

Fold

Molecule Type

Activation z-score

P Value

NFKBIA

−1.596

transcription regulator

−2.377

0.000129

MYC

−1.511

transcription regulator

2.359

1.79E-09

XBP1

1.878

transcription regulator

2.593

1.86E-05

  1. The top three networks (network score > 40) and top three regulator effect networks (consistency score > 0, target number > 3, |z-score| > 2, p-value < 0.05) are shown. The top five activated (z-score > 2) and inhibited (z-score < − 2) upstream regulators and master regulators in causal networks are shown (|fold change| > 1.5, |z-score| > 2, p-value < 0.05). Only upstream regulators and master regulators exhibiting differential expression between C2 and SR groups are displayed