Table 2 DEGs significantly enriched in neuroactive ligand-receptor interactions pathway

hypothalamus

KNG1↑

GPR83↓

PTGDR↓

PTGER4↑

PTRFR↓

LPAR3↑

VIPR1↑

CCKAR↓

GABRA6↓

CHRNA5↑

CHRNA2↓

pituitary

CHRM2↑

ADRA2B↑

HPH↑

HTR2A↑

HTR1F↑

HTR1D↑

HTR1B↑

HTR1E↓

AGTR↑

GRP↑

EDN2↑

MC5R↑

MTNR1B↑

S1PR1↑

INSL5↑

CALCB↑

CRH↑

CRHR2↑

GIP↑

GLP1R↑

GRM5↑

GRM7↑

GABBR2↑

GABRA6↑

GABRG2↑

CHRNA7↑

GRIK1↑

VIPR2↑

ovary stroma

DRD1↑

DRD3↓

CHRM4↓

CCKBR↓

GALR1↓

GALR2↓

POMC↑

TAC1↑

TAC4↑

AVPR1A↓

CGA↑

RXFP↓

GABRA5↑

GABRG3↑

CHRNA4↓

GRIK3↑

P2RX1↓

F5 follicle membrane

GABRG3↑

SSTR1↑

OPRN1↓