Table 3 The key DEGs enriched in HPG axis-related tissues
Tissue | Type | Cluster 22 | Cluster 25 | Cluster 35 | Cluster 8 |
|---|---|---|---|---|---|
Hypothalamus | SP | SEMA3A↑,SPAG17↑ |  |  | NMB↓ |
LUM↑,VEGFC↑ | ADAMTS15↓ | ||||
Pituitary | SP&TP | MMP28↑,SLIT2↑ | BMP2↓ | THBS1↓ | ADAMTS2↓ |
RBP3↑ | AMBP↓ | ||||
SPARC↑ |  | ||||
SP | PCSK2↑ |  | SCNN1A↓ |  | |
METRN↑ | |||||
IGFBP4↑ | |||||
0vary stroma | TP | FAM19A2↑,ISL1↑ | DLX1↓ | KCNMA1↓ | PVALB↓ |
CDX2↑,PAX9↑ | CHRDL1↓ | F5↓ | CCKBR↓ | ||
OSR2↑,FGG↑ | MGP↓ | IGF1↓ | AVPR1A↓ | ||
CADPS↑,FIGNL1↑ | CD34↓ | ACTN1↓ | ADAMTSL2↓ | ||
|  |  | THBS2↓ | ADAMTS8↓ | ||
F5 follicle membrane | TP | GAD2↑ |  |  |  |