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Table 2 The most enriched 10 KEGG pathways in either up- or down-regulated genes in each tissue in the comparison between individuals

From: Gene expression profiles provide insights into the survival strategies in deep-sea mussel (Bathymodiolus platifrons) of different developmental stages

 

Genes up-regulated in the older individual

Genes up-regulated in the younger individual

Map ID

Pathway description

p.adjust

Map ID

Pathway description

p.adjust

Gill

map03010

Ribosome a[M]

7.2E-04

map05200

Pathways in cancer a

7.7E-05

map04141

Protein processing in endoplasmic reticulum a[M]

1.5E-02

map05145

Toxoplasmosis a[I]

7.7E-05

map00230

Purine metabolism a[M]

1.5E-02

map05206

MicroRNAs in cancer a

7.7E-05

map00240

Pyrimidine metabolism a[M]

1.5E-02

map04510

Focal adhesion a

8.3E-05

map00260

Glycine, serine and threonine metabolism a[M]

2.3E-02

map04064

NF-kappa B signaling pathway a

8.3E-05

map04730

Long-term depression a

2.6E-02

map05222

Small cell lung cancer a

8.3E-05

map04341

Hedgehog signaling pathway a

2.8E-02

map04668

TNF signaling pathway a[I]

8.3E-05

map00290

Valine, leucine and isoleucine biosynthesis a[M]

2.8E-02

map05164

Influenza A a[I]

9.4E-05

map00300

Lysine biosynthesis a[M]

2.8E-02

map04621

NOD-like receptor signaling pathway a[I]

1.0E-04

map04742

Taste transduction

6.2E-02

map04215

Apoptosis - multiple species a

2.1E-04

Mantle

map04141

Protein processing in endoplasmic reticulum a[M]

1.6E-04

map05145

Toxoplasmosis a[I]

1.3E-04

map00230

Purine metabolism a[M]

1.7E-03

map04621

NOD-like receptor signaling pathway a[I]

1.3E-04

map04742

Taste transduction a

1.7E-03

map04624

Toll and Imd signaling pathway a[I]

4.1E-04

map04730

Long-term depression a

4.3E-03

map04668

TNF signaling pathway a

5.8E-04

map04341

Hedgehog signaling pathway a

1.2E-02

map04215

Apoptosis - multiple species a

1.2E-03

map03010

Ribosome a[M]

1.2E-02

map05222

Small cell lung cancer a

4.7E-03

map00260

Glycine, serine and threonine metabolism a[M]

1.2E-02

map05134

Legionellosis a[I]

6.4E-03

map05110

Vibrio cholerae infection a[I]

3.0E-02

map05152

Tuberculosis a[I]

2.1E-02

map00240

Pyrimidine metabolism a[M]

3.1E-02

map04640

Hematopoietic cell lineage a[I]

2.1E-02

map00290

Valine, leucine and isoleucine biosynthesis a[M]

3.2E-02

map01524

Platinum drug resistance a[I]

2.6E-02

Adductor muscle

map03010

Ribosome a[M]

9.3E-14

map05100

Bacterial invasion of epithelial cells a[I]

2.2E-07

map03050

Proteasome a[M]

3.9E-05

map04810

Regulation of actin cytoskeleton a

9.6E-07

map04141

Protein processing in endoplasmic reticulum a[M]

9.8E-03

map05131

Shigellosis a

3.3E-06

map00020

Citrate cycle (TCA cycle)

5.1E-02

map05120

Epithelial cell signaling in Helicobacter pylori infection a[I]

1.5E-04

map00740

Riboflavin metabolism

5.1E-02

map05130

Pathogenic Escherichia coli infection a[I]

1.8E-04

map03060

Protein export

5.1E-02

map04666

Fc gamma R-mediated phagocytosis a[I]

1.8E-04

map05150

Staphylococcus aureus infection

5.1E-02

map00190

Oxidative phosphorylation a

2.6E-04

map00500

Starch and sucrose metabolism

5.1E-02

map04670

Leukocyte transendothelial migration a[I]

5.0E-04

map04721

Synaptic vesicle cycle

5.6E-02

map04530

Tight junction a

8.0E-04

map05110

Vibrio cholerae infection

6.4E-02

map04932

Non-alcoholic fatty liver disease (NAFLD) a

1.6E-03

  1. [M]: Pathways involved in metabolism or genetic information processing
  2. [I]: Pathways involved in infectious diseases or immune system
  3. a Significantly enriched pathways