Table 2 The results of KEGG pathway analysis of 248 DEGs that fulfilled the selection criteria of |log2FC|≥ 2 and adjusted P-value < 0.001
Group | KEGG pathway term | P-value | Genes |
|---|---|---|---|
Up-regulated genes | nd | nd | nd |
Down-regulated genes | Cytokine-cytokine receptor interaction | 3.80E-06 | BMP2, CCL11, CCL5, CSF2, INHBB, IL11, IL2RG, IL20RB, IL23A, IL7R, LTA, LTB, TNFSF15, TNFRSF4, TNFRSF9 |
Hematopoietic cell lineage | 4.60E-03 | CSF2, ITGAM, IL11, IL7R, HLA-DRA, HLA-DRB1 | |
Asthma | 5.70E-03 | CCL11, HLA-DOA, HLA-DRA, HLA-DRB1 | |
Pathways in cancer | 8.10E-03 | CBLC, BIRC3, BMP2, FGF21, KLK3, LAMB3, LAMC2, MMP9, SHH, WNT7B, WNT9A | |
Jak-STAT signaling pathway | 1.40E-02 | CBLC, CSF2, IL11, IL2RG, IL20RB, IL23A, IL7R | |
Type I diabetes mellitus | 1.60E-02 | LTA, HLA-DOA, HLA-DRA, HLA-DRB1 | |
ErbB signaling pathway | 2.50E-02 | CBLC, SHC2, AREG, EREG, HBEGF | |
Basal cell carcinoma | 3.30E-02 | BMP2, SHH, WNT7B, WNT9A | |
Hedgehog signaling pathway | 3.40E-02 | BMP2, SHH, WNT7B, WNT9A |