Fig. 3

Comparison of transcriptomic and functional response in response to T3SS and T6SS P. aeruginosa mutants. A Venn diagram of differentially expressed epithelial genes. Only genes with a p-value ≤ 0.05, fold change > 2, and average FPKM difference > 7 were analyzed as differentially regulated genes. B Comparison of GO term analysis of “biological processes” of epithelial cells positively enriched in response to P. aeruginosa PA14 (PA14), heat-killed P. aeruginosa PA14 (HK), P. aeruginosa PA14::pscC (T3SS), and P. aeruginosa PA14 ΔHSI-II : : III (T6SS). Only GO terms with p ≤ 0.05 and number of genes associated with GO term > 5 is shown. The node color indicates the significance of functionally enriched GO terms in each group. The node size correlates with number of genes associated with functionally enriched GO terms