Skip to main content

Table 2 Immediate-early response gene dataset

From: P. aeruginosa type III and type VI secretion systems modulate early response gene expression in type II pneumocytes in vitro

Gene
symbol
Official full name Fold change P value Refs
EGR1 Early growth response 1 28.41 2.17 × 10–24 [16, 17]
FOS Fos proto-oncogene, AP-1 transcription factor subunit 17.47 9.93 × 10–17 [16, 17]
FOSB FosB proto-oncogene, AP-1 transcription factor subunit 7.39 1.05 × 10–5 [16, 17]
NR4A2 Nuclear receptor subfamily 4 group A member 2 4.39 5.95 × 10–7 [16]
ATF3 Activating transcription factor 3 3.51 1.02 × 10–5 [16, 22]
IL6 Interleukin 6 3.50 3.66 × 10–3 [16, 22]
NR4A1 Nuclear receptor subfamily 4 group A member 1 3.38 2.92 × 10–3 [16]
KLF6 Kruppel like factor 6 3.22 2.50 × 10–22 [22, 23]
GDF15 Growth differentiation factor 15 2.92 4.31 × 10–3 [22]
IER2 Immediate early response 2 2.68 9.76 × 10–14 [17, 22]
MAFF MAF bZIP transcription factor F 2.57 4.75 × 10–5 [22]
TRIB1 Tribbles pseudokinase 1 2.52 1.15 × 10–8 [17]
DUSP5 Dual specificity phosphatase 5 2.50 1.76 × 10–5 [16]
FOSL1 FOS like 1, AP-1 transcription factor subunit 2.47 6.45 × 10–3 [22, 24]
PTGS2 Prostaglandin-endoperoxide synthase 2 2.46 3.51 × 10–4 [22, 25, 26]
PHLDA1 Pleckstrin homology-like domain family A member 1 2.44 6.94 × 10–10 [27, 28]
ZFP36 ZFP36 ring finger protein 2.32 7.91 × 10–10 [16]
DUSP6 Dual specificity phosphatase 6 2.32 8.04 × 10–4 [16]
EREG Epiregulin 2.30 5.69 × 10–5 [27, 29]
GEM GTP binding protein overexpressed in skeletal muscle 2.29 3.09 × 10–6 [16]
IER3 Immediate early response 3 2.26 1.00 × 10–9 [16, 17]
BDNF Brain derived neurotrophic factor 2.21 9.78 × 10–4 [22, 30]
NR4A3 Nuclear receptor subfamily 4 group A member 3 2.24 4.43 × 10–2 [16]
KLF4 Kruppel like factor 4 2.15 7.92 × 10–4 [23]
LDLR Low density lipoprotein receptor 2.07 1.11 × 10–4 [16, 22]
RHOB Ras homolog family member B 1.98 2.13 × 10–2 [31]
KLF2 Kruppel like factor 2 1.97 2.73 × 10–2 [22, 23]
HES1 Hes family bHLH transcription factor 1 1.82 6.19 × 10–4 [22]