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Fig. 2 | BMC Genomics

Fig. 2

From: Deep learning for de-convolution of Smad2 versus Smad3 binding sites

Fig. 2

Characterization of Smad2 and Smad3 binding sites using DNAShapeR. A. Minor grove width (MGW) of Smad2-bound sites (left) and Smad3-bound sites (right). While both Smad2 and Smad3 had similar MGW at the centers of the peaks, there was a marked difference in the MGW 100 base pairs upstream and downstream of the peak center, with Smad3-bound peaks narrower than Smad2-bound. B. Electrostatic potential (EP) of Smad2- and Smad3-bound sites. Smad2-bound sites (left) were observed to have higher electrostatic potential when compared to Smad3-bound sites across the full 200 base pairs of each binding site

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