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Fig. 8 | BMC Genomics

Fig. 8

From: Integrative analysis of summary data from GWAS and eQTL studies implicates genes differentially expressed in Alzheimer’s disease

Fig. 8

Flowchart outlining the instrumental variable procedure of SMR. Known relationships represented by eQTL between genetic variants and gene expression and GWAS between genetic variants and AD are represented by solid arrows. The gene expression - AD (causal) relationship that we are trying to establish via SMR is represented by a dotted-line arrow

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BMC Genomics

ISSN: 1471-2164

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