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Table 1 This table shows the relevant cis-eQTL and summary GWAS p-values factored in to our SMR analysis. The index/ leftmost column includes both the gene analyzed along with the SNP with the strongest associations with both gene expression and our AD phenotype; these are the gene and SNP directly analyzed via SMR via the instrumental variables estimation. The first data column (denoted cis-eQTLa) contains the cis-eQTLp-values used from [29]; the final three data columns (denoted GWASb, GWASc, and GWASd) contain the summary GWASp-values used (from [11], [10], and [9], respectively); note these are different

From: Integrative analysis of summary data from GWAS and eQTL studies implicates genes differentially expressed in Alzheimer’s disease

Gene

SNP

cis-eQTLa

GWASb

GWASc

GWASd

PVR

rs11540084

2.57E-30

5.12E-8

1.87E-8

1.90E-6

TOMM40

rs7259620

4.05E-22

4.99E-148

5.78E-216

3.25E-125

NDUFS2

rs4379692

4.12E-19

3.02E-2

7.84E-8

8.07E-2

ZNF296

rs8100183

4.81E-11

4.52E-10

2.21E-8

8.25E-6

SNX32

rs17854357

<1.00E-300

3.50E-1

3.12E-6

1.33E-1

PRSS36

rs1549299

3.36E-18

1.14E-2

6.87E-8

3.21E-3

CEACAM19

rs714948

7.00E-20

1.35E-16

1.14E-25

6.26E-13

HLADRB1

rs9271069

1.79E-95

1.10E-3

2.26E-2

7.53E-8

CR1

rs679515

2.10E-18

1.55E-16

6.83E-19

4.10E-15

AC012146.7

rs73976310

6.19E-31

2.14E-2

6.50E-8

5.92E-4

CTB171A8.1

rs55710026

<1.00E-300

9.32E-13

5.59E-16

8.00E-16

RP11−385F7.1

rs9473119

2.67E-13

1.87E-7

1.02E-8

4.59E-8