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Fig. 2 | BMC Genomics

Fig. 2

From: Diabetes risk loci-associated pathways are shared across metabolic tissues

Fig. 2

Tissue shared eQTLs for diabetes-associated SNPs. a Overlap between expression, protein (cis), protein (trans) and metabolite QTLs. b QTL effects of rs474513 on SLC22A3 and LPA c Effect of rs474513 on LPA mRNA expression in the liver. X-axis, genotype; y-axis, normalized expression levels. d Effect of rs474513 on SLC22A3 mRNA expression in the liver. X-axis, genotype; y-axis, normalized expression levels. e Volcano plot of all the 1619 calculated eQTL—eGene pairs, with the tissue-shared eQTL highlighted. X-axis, normalized effect size; y-axis, P-value. Dots with similar colors represent the same eQTLs in multiple tissues

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