Assessment of a polygenic hazard score for the onset of pre-clinical Alzheimer’s disease

Table 3 Associations between PHS and cognitive decline

Population	N	Domain	beta	SE	CI 95%	p
CN + MCI	697	CDR SoB	0.004	0.014	[0.023–0.03]	0.747
		Episodic Recall	0.007	0.011	[−0.014–0.028]	0.519
		Executive Function	− 0.023	0.014	[− 0.05–0.003]	0.086
CN	573	CDR SoB	0.023	0.017	[−0.01–0.056]	0.174
		Episodic Recall	0.001	0.013	[−0.024–0.026]	0.948
		Executive Function	−0.018	0.015	[−0.047–0.011]	0.225