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Table 4 Details of the 14 single nucleotide polymorphisms (SNPs) detected in the common OAR1 region associated with body reserves at four physiological stages

From: Genome-wide analyses reveal a strong association between LEPR gene variants and body fat reserves in ewes

SNP

Position

MAF

P-value

Gene

Variant type

BCS-Pa

BCS-Pb

BCS-L

BCS-Sa

OAR1_41661218.1

40,268,642

0.39

3.05E-05

1.91E-05

7.40E-07

5.71E-04

no

intergenic

s30054.1

40,524,081

0.09

2.51E-06

3.28E-04

2.75E-03

3.21E-04

no

intergenic

OAR1_42038601.1

40,539,479

0.36

2.72E-05

3.06E-05

4.58E-06

1.41E-02

no

intergenic

oar3_OAR1_40821987

40,821,987

0.35

3.42E-05

2.74E-06

1.88E-05

8.63E-07

LEPR

intron

oar3_OAR1_40828247

40,828,247

0.44

1.55E-05

3.61E-07

6.81E-07

3.50E-06

LEPR

intron

oar3_OAR1_40848298

40,848,298

0.32

2.72E-05

1.27E-07

4.11E-08

4.32E-05

LEPR

intron

oar3_OAR1_40,857,869

40,857,869

0.32

2.72E-05

1.27E-07

4.11E-08

4.32E-05

LEPR

missence

oar3_OAR1_40865586

40,865,586

0.32

2.72E-05

1.27E-07

4.11E-08

4.32E-05

no

intergenic

oar3_OAR1_40872161

40,872,161

0.50

1.10E-02

4.60E-04

6.76E-06

3.83E-04

no

intergenic

oar3_OAR1_40890859

40,890,859

0.32

6.15E-05

3.31E-07

3.61E-08

6.09E-05

no

intergenic

oar3_OAR1_41137040

41,137,040

0.31

1.33E-05

1.17E-06

6.10E-07

2.50E-04

no

intergenic

OAR1_43022391.1

41,454,757

0.28

2.61E-04

8.85E-05

1.04E-06

2.55E-04

no

intergenic

OAR1_43083702.1

41,512,082

0.62

1.05E-03

1.41E-04

1.02E-05

1.15E-06

no

intergenic

oar3_OAR1_41564208

41,564,208

0.61

3.34E-06

8.10E-05

7.10E-07

3.77E-04

no

intergenic

  1. SNP Name of the single nucleotide polymorphism, MAF minor allele frequency, BCS Body Condition Score; P-value, the p-values reported correspond to the unadjusted p-value from the Wald test. In bold, SNP significant at the genome-wide threshold; in italics, non-significant SNPs at the chromosome-wide threshold. Gene, gene is reported when SNP overlapped with a gene. LEPR, Leptin receptor